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Komplekst regionalt smertesyndrom (CRPS)

Et regionalt smertesyndrom er lokalisert til et avgrenset område av kroppen, oftest i underarmen eller leggen. I de fleste tilfeller er det en følgetilstand etter en akutt skade.

Et regionalt smertesyndrom kan skyldes forstyrrelser i det sympatiske nervesystemet, den delen av nervesystemet som ikke er viljestyrt, og som kontrollerer smerteimpulser, blodstrømmen og svettekjertlene dine.

Sist oppdatert:

14. sep. 2021

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Komplekst regionalt smertesyndrom . Referanselisten for dette dokumentet vises nedenfor

  1. Abdi S. Complex regional pain syndrome in adults: Pathogenesis, clinical manifestations, and diagnosis. UpToDate, last updated Jul 13, 2020. www.uptodate.com
  2. Maihöfner C, Seifert F, Markocic K. Complex regional pain syndromes: new pathophysiological concepts and therapies. Eur J Neurol 2010; 17: 649-60. PubMed
  3. Kambskard Petersen G, Reinhold Jensen M, Dahlin LB, Søe Nielsen NH. Refleksdystrofi. Ugeskr Læger 2002; 164: 5019-24. PubMed
  4. Shim H, Rose J, Halle S, Shekane P. Complex regional pain syndrome: a narrative review for the practising clinician. Br J Anaesth. 2019 Aug;123(2):e424-e433. Epub 2019 May 2. PMID: 31056241. PubMed
  5. Petersen PB, Mikkelsen KL, Lauritzen JB, Krogsgaard MR. Risk factors for post-treatment complex regional pain syndrome (CRPS): an analysis of 647 cases of CRPS from the Danish Patient Compensation Association. Pain Pract. 2018;18(3):341-349. PMID: 28691184.
  6. Kim H, Lee CH, Kim SH, Kim YD. Epidemiology of complex regional pain syndrome in Korea: An electronic population health data study. PLoS One. 2018 Jun 4;13(6):e0198147. Erratum in: PLoS One. 2018 Jul 23;13(7):e0201327. PMID: 29864152. PubMed
  7. Shenker N, Chhabra G. Complex regional pain syndrome. BMJ Best Practice. Last reviewed 16 Sep 2020. bestpractice.bmj.com
  8. Eldufani J, Elahmer N, Blaise G. A medical mystery of complex regional pain syndrome. Heliyon. 2020 Feb 19;6(2):e03329. PMID: 32149194. PubMed
  9. Koman LA, Smith BP, Ekman EF, Smith TL. Complex regional pain syndrome. Instr Course Lect 2005; 54: 11-20. PubMed
  10. Birklein F, Ajit SK, Goebel A, Perez RSGM, Sommer C. Complex regional pain syndrome - phenotypic characteristics and potential biomarkers. Nat Rev Neurol. 2018 May;14(5):272-284. Epub 2018 Mar 16. PMID: 29545626.
  11. Harden RN, McCabe CS, Goebel A et al. Complex Regional Pain Syndrome: Practical Diagnostic and Treatment Guidelines, 5th Edition. Pain Med. 2022 Jun 10;23(Suppl 1):S1-S53. PMID: 35687369 PubMed
  12. Wüppenhorst N, Maier C, Frettlöh J, et al. Sensitivity and specificity of 3-phase bone scintigraphy in the diagnosis of complex regional pain syndrome of the upper extremity. Clin J Pain 2010; 26: 182. PubMed
  13. Birklein F, O'Neill D, Schlereth T. Complex regional pain syndrome: An optimistic perspective. Neurology 2015; 84: 89. PMID: 25471395 PubMed
  14. Wasner G, Schattschneider J, Baron R. Skin temperature side differences--a diagnostic tool for CRPS? Pain 2002; 98: 19-26. PubMed
  15. Birklein F, Dimova V. Complex regional pain syndrome-up-to-date. Pain Rep. 2017 Oct 5;2(6):e624. PMID: 29392238. PubMed
  16. Kalita J, Vajpayee A, Misra UK. Comparison of prednisolone with piroxicam in complex regional pain syndrome following stroke: a randomized controlled trial. QJM 2006; 99: 89-95. PubMed
  17. Zyluk A, Puchalski P. Treatment of early complex regional pain syndrome type 1 by a combination of mannitol and dexamethasone. J Hand Surg Eur Vol 2008; 33: 130-6. pmid:18443050 PubMed
  18. Varenna M1, Adami S, Rossini M, et al. Treatment of complex regional pain syndrome type I with neridronate: a randomized, double-blind, placebo-controlled study. Rheumatology (Oxford) 2013; 52: 534-42. pmid:23204550 PubMed
  19. Daly AE, Bialocerkowski AE. Does evidence support physiotherapy management of adult Complex Regional Pain Syndrome Type One? A systematic review. Eur J Pain 2009; 13: 339-53. pmid:18619873 PubMed
  20. Smart KM, Wand BM, O'Connell NE. Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II. Cochrane Database Syst Rev. 2016 Feb 24;2:CD010853 . pmid:26905470 PubMed
  21. SBU. Behandling vid komplext regionalt smärtsyndrom. 2022-06-27 (Hämtad 2022-08-01). www.sbu.se
  22. Rosted P, Kragh Jørgensen VR. Posttraumatisk refleksdystrofi - er akupunktur en mulighed?. Ugeskr Læger 2004; 166: 3004-5. PubMed
  23. Stanton TR, Wand BM, Carr DB, Birklein F, Wasner GL, O'Connell NE. Local anaesthetic sympathetic blockade for complex regional pain syndrome. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD004598. DOI: 10.1002/14651858.CD004598.pub3. DOI
  24. Shibuya N, Humphers JM, Agarwal MR, Jupiter DC. Efficacy and safety of high-dose vitamin C on complex regional pain syndrome in extremity trauma and surgery--systematic review and meta-analysis. J Foot Ankle Surg 2013; 52: 62. PubMed
  25. Bean DJ, Johnson MH, Heiss-Dunlop W, Kydd RR. Extent of recovery in the first 12 months of complex regional pain syndrome type-1: A prospective study. Eur J Pain. 2016;20(6):884-894. PubMed
  26. Ljøstad U. Komplekst regionalt smertesyndrom (CRPS). I NevroNEL - nevrologisk prosedyrer. Sist oppdatert 28.10.2020. Siden leste 14.9.2021. nevrologi.legehandboka.no
  27. NIH. Complex Regional Pain Syndrome Fact Sheet. Last updated sept. 2020. Siden lest 14.09.2021. www.ninds.nih.gov
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