NHI.no
Annonse
Informasjon

Alkoholavhengighet

Alkoholavhengiget er en tilstand kjennetegnet av tap av kontroll over alkoholforbruket.

Alkohol virker på hjernen på mange ulike måter - blant annet i form av "tregere" tankegang og reflekser og dårligere dømmekraft.

Sist oppdatert:

10. jan. 2023

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Alkoholavhengighet . Referanselisten for dette dokumentet vises nedenfor

  1. Skjøtskift S. Alkohol som medvirkende faktor i noen vanlige kliniske situasjoner. Tidsskr Nor Lægeforen 2003; 123: 185-7. PubMed
  2. Folkehelserapporten. Rusbrukslidelser i Norge. Folkehelseinstituttet, oppdatert 06.12.2019. fhi.no
  3. O`Dowd. Alcohol accounts for 6% of all admissions til English hospitals. BMJ 2008; 337: a963. PubMed
  4. Tolstrup JS, Nordestgaard BG, Rasmussen S, Tybjærg-Hansen A, Grønbæk M. Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme - sekundærpublikation. Ugeskr Læger 2008; 170: 2672. PubMed
  5. Schumann G, Liu C, O'Reilly P, et al. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Proc Natl Acad Sci USA 2016; 113:14372. doi: 10.1073/pnas.1611243113 DOI
  6. Tvedt H, Stokke R, Lid TH, Selbekk AS. Problematisk alkoholbruk etter fedmekirurgi – en kvalitativ studie. Tidsskr Nor Legeforen 2023. doi:10.4045/tidsskr.22.0449 DOI
  7. Torvik FA, Ystrom E, Gustavson K, et al. Diagnostic and genetic overlap of three common mental disorders in structured interviews and health registries. Acta Psychiatr Scand. 2018 Jan;137(1):54-64. PMID: 29072781. PubMed
  8. Brown RL, Saunders LA, Bobula JA, Lauster MH. Remission of alcohol disorders in primary care patients. J Fam Pract 2000; 49: 522-8. PubMed
  9. Braut GS. Krav til rusmiddelarbeid i helsetenesta. Tidsskr Nor Lægeforen 2003; 123: 49-51. PubMed
  10. Nordlie E. Alkoholmisbruk - hvilke konsekvenser har det for familiemedlemmene?. Tidsskr Nor Lægeforen 2003; 123: 52-4. PubMed
  11. Winslow BT, Onysko M. Medications for alcohol use disorder. Am Fam Physician. 2016 Mar 15;93(6):457-465.
  12. Jonas DE, Amick HR, Feltner C, et al. Pharmacotherapy for adults with alcohol use disorders in outpatient settings. A systematic review and meta-analysis. JAMA 2014; 311: 1889-900. doi:10.1001/jama.2014.3628. DOI
  13. Pettinati HM, Oslin DW, Kampman KM, et al. A double-blind, placebo-controlled trial combining sertraline and naltrexone for treating co-occuring depression and alcohol dependence. Am J Psychiatry 2010; 167: 668-75. American Journal of Psychiatry
  14. Pani PP, Trogu E, Pacini M, et al. Anticonvulsants for alcohol dependence. Cochrane Database Syst Rev. 2014 Feb 13;2:CD008544. The Cochrane Library
  15. Malcolm R, Myrick H, Roberts J, Wang W, Anton RF, Ballenger JC. The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial. J Gen Intern Med 2002; 17: 349-55. PubMed
  16. Johnson BA, Ait-Daoud N, Bowden CL, et al. Oral topiramate for treatment of alcohol dependence: a randomised controlled trial . Lancet 2003; 361: 1677-85. PubMed
  17. Bogenschutz MP, Ross S, Bhatt S, et al. Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder A Randomized Clinical Trial. JAMA Psychiatry 2022; 79: 953-962. pmid:36001306 PubMed
  18. Rösner S, Hackl-Herrwerth A, Leucht S, Vecchi S, Srisurapanont M, Soyka M. Opioid antagonists for alcohol dependence. Cochrane Database of Systematic Reviews 2010, Issue 12. Art. No.: CD001867. DOI: 10.1002/14651858.CD001867.pub3. DOI
  19. Carmen B, et al. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction 2004; 99: 811-28. PubMed
  20. Berglund M, Thelander S, Salaspuro M et al. Treatment of alcohol abuse: An evidence-based review. Alcohol Clin Exp Res 2003; 27: 1645-56. PubMed
  21. Anton RF, O’Malley SS, Ciraulo DA, et al. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE Study: a randomized controlled trial. JAMA 2006; 295: 2003-17. Journal of the American Medical Association
  22. Bouza C, Magro A, Munoz A, Amate J. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction 2004; 99: 811-8. PubMed
  23. Palpacuer C, Laviolle B, Boussageon R, et al. Risks and benefits of nalmefene in the treatment of adult alcohol dependence: A systematic literature review and meta-analysis of published and unpublished double-blind randomized controlled trials. PLoS Med. 2015. doi: 10.1371/journal.pmed.1001924 DOI
  24. Mørland J. Legemidler mot alkoholmisbruk. Tidsskr Nor Lægeforen 2006; 126: 3268-9. PubMed
  25. Heilig M, Egli M. Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms. Pharmacol Ther 2006; 111: 855-76. PubMed
  26. Rosner S, Hackl-Herrwerth A, Leucht S, et al. Acamprosate for alcohol dependence. Cochrane Database of Systematic Reviews 2010; 9: CD004332. Cochrane (DOI)
  27. Jonas DE, Amick HR, Feltner C, et al. Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings. A Systematic Review and Meta-analysis. JAMA. 2014 14;311(18):1889-900. doi: 10.1001/jama.2014.3628. DOI
  28. Mann K, Lehert P, Morgan MY. The efficacy of acamprosate in the maintenance of abstinence in alcohol dependent individuals: Results of a metaanalysis. Alcohol Clin Exp Res 2004; 28: 51-63. PubMed
  29. Namkoong K, Lee BQ, Lee PG et al. Acamprosate in Korean alcohol-dependent patients: A multi-centre, randomized, double-blind, placebo controlled study. Alcohol Alcohol 2003; 28: 135 - 41. PubMed
  30. Johnson BA, Rosenthal N, Capece JA, et al, for the Topiramate for Alcoholism Advisory Board and the Topiramate for Alcoholism Study Group. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA 2007; 298: 1641-51. Journal of the American Medical Association
  31. Mason BJ, Quello S, Goodell V, et al. Gabapentin treatment for alcohol dependence: A randomized clinical trial. JAMA Intern Med 2013. doi:10.1001/jamainternmed.2013.11950 DOI
  32. Zhao J, Stockwell T, Naimi T, et al. Association Between Daily Alcohol Intake and Risk of All-Cause Mortality A Systematic Review and Meta-analyses. JAMA Netw Open 2023; 6: e236185. pmid:PMID: 37000449 PubMed
  33. Foster T. Editorial. Dying for a drink. BMJ 2001; 323: 817-8. PubMed
  34. Esser MB, Leung G, Sherk A, et al. Estimated Deaths Attributable to Excessive Alcohol Use Among US Adults Aged 20 to 64 Years, 2015 to 2019. JAMA Netw Open 2022. doi:10.1001/jamanetworkopen.2022.39485 DOI
Annonse
Annonse